Quantifying Cellular Reaction to Geometric Properties of Extracellular Environment

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dato

BEMÆRK: Ansøgningsfristen er overskredet

Applicants are invited for a PhD fellowship/scholarship at Graduate School of Technical Sciences, Aarhus University, Denmark, within the Biological and Chemical Engineering programme. The position is available as soon as possible.

Title:
Quantifying Cellular Reaction to Geometric Properties of Extracellular Environment

Research area and project description:
The latest advancements in stem cell engineering reveal that modifications to the way cells exchange forces play a crucial role in cell physiology. However, the underlying mechanisms through which cells perceive and respond to mechanical signals from their surrounding environment, specifically its microstructural geometry, remain elusive. Understanding these fundamental mechanobiological mechanisms will have a significant impact on biotechnology. This project aims to harness the power of nanoporous biomaterials, which can be manipulated to control their microstructural arrangement, thereby allowing us to modulate the mechanical environment of individual cells growing on or within the material.

Our goal is to shed light on the mechanisms of force exchange between cells and their environment. To accomplish this, we are utilizing synchrotron-generated X-Ray tomography to capture 3D images of cells grown in different nanostructures. Our project aims to develop a mathematical model that identifies key morphological characteristics of the material's microstructure. To do so, we will utilize methods from stereology, stochastic geometry, and biomechanics to analyze the data. You can read more about the project here: www.mechanogeometry.au.dk

Project description: For technical reasons, you must upload a project description. Please simply copy the project description above, and upload it as a PDF in the application.

Qualifications and specific competences:
The successful candidate must have a Master’s degree in Chemistry, Chemical engineering, materials science or a similar subject. Experience with finite element analysis of materials and biology will be considered beneficial.

Place of employment and place of work:
The place of employment is Aarhus University, and the place of work is Department of Biological and Chemical Engineering, Gustaw Vieds vej 12, DK-8000 Aarhus, Denmark.

Contacts:
Applicants seeking further information are invited to contact Associate Professor Jens Vinge Nygaard, jvn@bce.au.dk

How to apply:
Please follow this link to submit your application. Application deadline is Sunday, 18 June at 23:59 CEST. Preferred starting date is as soon as possible.

For information about application requirements and mandatory attachments, please see our application guide.

Please note:

  • The programme committee may request further information or invite the applicant to attend an interview.
  • Shortlisting will be used, which means that the evaluation committee only will evaluate the most relevant applications.

Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants. All interested candidates are encouraged to apply, regardless of their personal background. Salary and terms of employment are in accordance with applicable collective agreement.

 

INFORMATIONER OM STILLINGEN:

- Arbejdspladsen ligger i:

Aarhus Kommune

-Virksomheden tilbyder:

-Arbejdsgiver:

Aarhus Universitet, Nordre Ringgade 1, 8000 Aarhus C

-Ansøgning:

Ansøgningsfrist: 18-06-2023; - ansøgningsfristen er overskredet

Ved skriftlig henvendelse: https://app.researchplanner.net/Peoplexs22/CandidatesPortalNoLogin/ApplicationForm.cfm?PortalID=16581&VacatureID=1083033

Se mere her: https://job.jobnet.dk/CV/FindWork/Details/5845561

Denne artikel er skrevet af Emilie Bjergegaard og data er automatisk hentet fra eksterne kilder, herunder JobNet.
Kilde: JobNet